Protein name:
Heat shock protein 75 kDa, mitochondrial (HSP 75) ;
Alternative:
Tumor necrosis factor type 1 receptor-associated protein (TRAP-1) ;TNFR-associated protein 1 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Binds to the intracellular domain of tumor necrosis factor type 1 receptor. Binds to RB1.
Function:
Chaperone that expresses an ATPase activity.
Subcellular Location:
Mitochondrion
Protein Attributes:
50:
MARELRALLL | WGRRLRPLLR | APALAAVPGG | KPILCPRRTT | AQLGPRRNPA |
100:
WSLQAGRLFS | TQTAEDKEEP | LHSIISSTES | VQGSTSKHEF | QAETKKLLDI |
150:
VARSLYSEKE | VFIRELISNA | SDALEKLRHK | LVSDGQALPE | MEIHLQTNAE |
200:
KGTITIQDTG | IGMTQEELVS | NLGTIARSGS | KAFLDALQNQ | AEASSKIIGQ |
250:
FGVGFYSAFM | VADRVEVYSR | SAAPGSLGYQ | WLSDGSGVFE | IAEASGVRTG |
300:
TKIIIHLKSD | CKEFSSEARV | RDVVTKYSNF | VSFPLYLNGR | RMNTLQAIWM |
350:
MDPKDVREWQ | HEEFYRYVAQ | AHDKPRYTLH | YKTDAPLNIR | SIFYVPDMKP |
400:
SMFDVSRELG | SSVALYSRKV | LIQTKATDIL | PKWLRFIRGV | VDSEDIPLNL |
450:
SRELLQESAL | IRKLRDVLQQ | RLIKFFIDQS | KKDAEKYAKF | FEDYGLFMRE |
500:
GIVTATEQEV | KEDIAKLLRY | ESSALPSGQL | TSLSEYASRM | RAGTRNIYYL |
550:
CAPNRHLAEH | SPYYEAMKKK | DTEVLFCFEQ | FDELTLLHLR | EFDKKKLISV |
600:
ETDIVVDHYK | EEKFEDRSPA | AECLSEKETE | ELMAWMRNVL | GSRVTNVKVT |
650:
LRLDTHPAMV | TVLEMGAARH | FLRMQQLAKT | QEERAQLLQP | TLEINPRHAL |
700:
IKKLNQLRAS | EPGLAQLLVD | QIYENAMIAA | GLVDDPRAMV | GRLNELLVKA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Bovine
Human
Rat
ELISA Kit for Human HSP 75
ELISA Kit for Human HSP 75
ELISA Kit for Human HSP 75
ELISA Kit for Human HSP 75
CLIA Kit for Human HSP 75
CLIA Kit for Human HSP 75
CLIA Kit for Human HSP 75
CLIA Kit for Human HSP 75
Polyclonal Antibody for Human HSP 75
Polyclonal Antibody for Human HSP 75
Polyclonal Antibody for Human HSP 75
Polyclonal Antibody for Human HSP 75
Monoclonal Antibody for Human HSP 75
Monoclonal Antibody for Human HSP 75
Monoclonal Antibody for Human HSP 75
Monoclonal Antibody for Human HSP 75
R&D Technical Data
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Precision
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Recovery
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Linearity
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLY-307
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
tissue :
Eye .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 16-704;VARIANT GLY-307
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-494;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cell Metab.17:988-999(2013)
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION AS NEGATIVE REGULATOR OF MITOCHONDRIAL RESPIRATION;INTERACTION WITH SDHA
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"TRAP1 rescues PINK1 loss-of-function phenotypes."
Zhang L.
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Hum. Mol. Genet.22:2829-2841(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
14.
"Molecular chaperone TRAP1 regulates a metabolic switch between mitochondrial respiration and aerobic glycolysis."
Yoshida S.
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more...
Proc. Natl. Acad. Sci. U.S.A.110:E1604-E1612(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION AS NEGATIVE REGULATOR OF MITOCHONDRIAL RESPIRATION;INTERACTION WITH SRC;TISSUE SPECIFICITY;SUBCELLULAR LOCATION