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Index > Protein center > TRAP1(Gene name) > Human
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  • TRAP1 (Gene name),
  • Heat shock protein 75 kDa, mitochondrial (Protein name ),  TRAP1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TRAP1(HSP75);
    Protein name:
    Heat shock protein 75 kDa, mitochondrial(HSP 75);
    Alternative:
    Tumor necrosis factor type 1 receptor-associated protein(TRAP-1);TNFR-associated protein 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds to the intracellular domain of tumor necrosis factor type 1 receptor. Binds to RB1.
    Function:
    Chaperone that expresses an ATPase activity.
    Subcellular Location:
    Mitochondrion
    Protein Attributes:
    Sequence length:
    704
    Sequence:
    50:
    MARELRALLL | WGRRLRPLLR | APALAAVPGG | KPILCPRRTT | AQLGPRRNPA | 
    100:
    WSLQAGRLFS | TQTAEDKEEP | LHSIISSTES | VQGSTSKHEF | QAETKKLLDI | 
    150:
    VARSLYSEKE | VFIRELISNA | SDALEKLRHK | LVSDGQALPE | MEIHLQTNAE | 
    200:
    KGTITIQDTG | IGMTQEELVS | NLGTIARSGS | KAFLDALQNQ | AEASSKIIGQ | 
    250:
    FGVGFYSAFM | VADRVEVYSR | SAAPGSLGYQ | WLSDGSGVFE | IAEASGVRTG | 
    300:
    TKIIIHLKSD | CKEFSSEARV | RDVVTKYSNF | VSFPLYLNGR | RMNTLQAIWM | 
    350:
    MDPKDVREWQ | HEEFYRYVAQ | AHDKPRYTLH | YKTDAPLNIR | SIFYVPDMKP | 
    400:
    SMFDVSRELG | SSVALYSRKV | LIQTKATDIL | PKWLRFIRGV | VDSEDIPLNL | 
    450:
    SRELLQESAL | IRKLRDVLQQ | RLIKFFIDQS | KKDAEKYAKF | FEDYGLFMRE | 
    500:
    GIVTATEQEV | KEDIAKLLRY | ESSALPSGQL | TSLSEYASRM | RAGTRNIYYL | 
    550:
    CAPNRHLAEH | SPYYEAMKKK | DTEVLFCFEQ | FDELTLLHLR | EFDKKKLISV | 
    600:
    ETDIVVDHYK | EEKFEDRSPA | AECLSEKETE | ELMAWMRNVL | GSRVTNVKVT | 
    650:
    LRLDTHPAMV | TVLEMGAARH | FLRMQQLAKT | QEERAQLLQP | TLEINPRHAL | 
    700:
    IKKLNQLRAS | EPGLAQLLVD | QIYENAMIAA | GLVDDPRAMV | GRLNELLVKA | 
    704:
    LERH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    KEGG:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human HSP 75
    Cat.:
    E10312m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human HSP 75
    Cat.:
    E10312b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human HSP 75
    Cat.:
    E10312h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human HSP 75
    Cat.:
    E10312r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human HSP 75
    Cat.:
    U10312r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human HSP 75
    Cat.:
    U10312m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human HSP 75
    Cat.:
    U10312h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human HSP 75
    Cat.:
    U10312b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human HSP 75
    Cat.:
    P10312Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human HSP 75
    Cat.:
    P10312Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human HSP 75
    Cat.:
    P10312Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human HSP 75
    Monoclonal Antibody for Human HSP 75
    Monoclonal Antibody for Human HSP 75
    Monoclonal Antibody for Human HSP 75
    Monoclonal Antibody for Human HSP 75
    Protein for Human HSP 75
    Protein for Human HSP 75
    Protein for Human HSP 75
    Protein for Human HSP 75

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    Linearity
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    References
    1. 1.
      "A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses."
      Simmons A.D. , Musy M.M. , Lopes C.S. , Hwang L.-Y. , Yang Y.-P. , Lovett M.
      Hum. Mol. Genet.8:2155-2164(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLY-307
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    3. 3.
      "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
      Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
      tissue: Eye.
    6. 6.
      "Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor."
      Song H.Y. , Dunbar J.D. , Zhang Y.X. , Guo D. , Donner D.B.
      J. Biol. Chem.270:3574-3581(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 16-704;VARIANT GLY-307
    7. 7.
      "A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock."
      Chen C.-F. , Chen Y. , Dai K. , Chen P.-L. , Riley D.J. , Lee W.-H.
      Mol. Cell. Biol.16:4691-4699(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 53-704;VARIANT GLU-395
    8. 8.
      "The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties."
      Felts S.J. , Owen B.A.L. , Nguyen P. , Trepel J. , Donner D.B. , Toft D.O.
      J. Biol. Chem.275:3305-3312(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-494;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-332; LYS-424 AND LYS-466;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase."
      Sciacovelli M. , Guzzo G. , Morello V. , Frezza C. , Zheng L. , Nannini N. , Calabrese F. , Laudiero G. , Esposito F. , Landriscina M. , Defilippi P. , Bernardi P. , Rasola A.
      Cell Metab.17:988-999(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS NEGATIVE REGULATOR OF MITOCHONDRIAL RESPIRATION;INTERACTION WITH SDHA
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS NEGATIVE REGULATOR OF MITOCHONDRIAL RESPIRATION;INTERACTION WITH SRC;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
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